ISSN 1003-8280 CN 10-1522/R 中国疾病预防控制中心 主办
Objective To determine the effectiveness of Japanese encephalitis (JE) mass immunization campaign in Guizhou in 2008, providing evidence for the development of control strategies. Methods Comprehensive analysis was performed based on the reports and investigation results during mass immunization campaign and epidemic information from the National Diseases Reporting System before and after the launch. Results A total of 1 503 052 children were immunized, the reported immunization coverage being 96.72%, the estimated coverage based on the population data 91.82%. The provincial incidence of JE was 0.85/100 000 in 2008, a decrease of 44.08% compared to that in 2007. Sharp decline in the incidence among target population was observed in various areas and counties to a more significant extent than that in non-target population. The incidence also decreased in each age group in 2008, yet the 8?month to 6-year-old group still had the highest incidence. Above average level of incidence was seen in Anshun, Qianxinan, Tongren and Bijie, and an increase of 111.59% was present in Anshun when compared to that in 2007. The incidence rates of 7 to 10-year-old group in Anshun, Qianxinan were both above the provincial average level, which increased by 117.83% and 66.32% when compared to those in 2007. Conclusion The expected goal of the JE mass immunization campaign had been attained. Younger children, especially those aged 8 months to 6 years in the province, were still the key group for prevention and control of this disease. Importance should be attached to the prevention and control of JE in such key areas as Anshun and Qianxinan.
【Abstract】 Objective To explore control efficacy of one?dose Japanese encephalitis(JE) attenuated live vaccine in 1-3 years in JE endemic areas, and provide the evidence for its control. Methods The children who only inoculated one?dose JE attenuated live vaccine from 2004 to 2006 in Guizhou were investigated, and its incidence rate within 1-3 years after inoculation was analyzed. At the same time, the immunization retrospective study to all the JE confirmed cases was done. Results The incidence rate of JE immunization county declined 62.36% compared to that of last year, but it rebounded after inoculation for 1-2 years in some counties. Among the cases investigated, the targeted children accounted for 73.28%. No JE vaccine had been inoculated in 27 cases sampled randomly. The incidence rates of objectors were no significant difference after immunization for 1-3 years(χ2=0.73, P>0.05), which were 6.25/100 000, 5.77/100 000 and 4.54/100 000, respectively. The inoculation rates were 1.92% among 52 diagnosed cases, lower than that of the control(29.41%), and significant difference was found between them (χ2=52.74, P<0.01). Conclusion The long?term control efficacy of one dose JE attenuated live vaccine is very good after inoculation for 1-3 years , and the effective method to realize control efficacy is the increase of inoculation rate. The rebound of incidence rate was related to the actual inoculation rate in some counties after immunization for 1-2 years.